(edited)

EAO-CRC

Early Age Onset
Colorectal Cancer

SUMMIT

MAY 14 – 16, 2021

VIRTUAL EVENT

SAVING LIVES THROUGH APPLYING KNOWLEDGE

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PRESIDENTIAL WELCOME

PRESIDENTIAL WELCOME

It is with great pleasure that I announce the 7th Annual Early Age Onset Colorectal Cancer (EAO CRC) Summit will be held on May 14-16, 2021. While we were are all hoping for an in-person gathering this Spring and welcoming you to the City That Never Sleeps with open arms it looks like we will be gathering virtually once again. But, don’t worry we are working around the clock to bring you another phenomenal agenda that takes full advantage of all of the amazing things we have learned about digital event technology over the past 12 months! 

Each year the EAO CRC SUMMIT™ brings together stakeholders from around the world including clinicians representing leading academic medical centers; the EAO CRC advocacy community; and scientists and epidemiologists who lead research at prestigious institutes, universities, and companies worldwide. And, in May we will gather to exchange ideas, share knowledge, and advance our common cause of understanding EAO CRC on a truly global scale.

Our objective is to understand and advance the “state-of-the-science” – the latest information regarding national and international EAO CRC incidence trends, pathogenesis, and genetics; present cutting-edge medical and research advancements and breakthroughs; and build community, conversation, and action focused on addressing EAO CRC. In short, we are focused on saving lives through applying knowledge.​

Want to start an interdisciplinary program focused on EAO CRC? No problem – we’ve got you covered. Looking to learn the latest surgical advances in caring for rectal cancer patients from the best in the field? We’ve got that on the program, too!

​If you have a topic that you want to ensure is included in next year’s robust agenda, please let us know. You can reach me directly at borassi@legacy.coloncancerfoundation.org.

We are looking forward to seeing everyone in just a few short weeks. Please do share this information with a colleague – the more the merrier! See you soon – May 14-16, 2021 is right around the corner!

Until then be well,

Cindy

President, Colon Cancer Foundation

2021 SUMMIT SPONSORS

PLANNED PRESENTATIONS AND INVITED FACULTY INCLUDE

CRC 2019 BROCHURE

THURSDAY, MAY 2, 2019

7:00 AM – 8:00 AM REGISTRATION AND BREAKFAST

8:00 AM – 8:30 AM FRAMING THE CONVERSATION: STRATEGIC CHALLENGES IN CURRENT MEDICAL CARE THAT CONTRIBUTE TO YOUNG ADULT COLORECTAL CANCER (CRC) INCIDENCE AND MORTALITY. SURVIVOR TESTIMONIALS UNDERSCORE OPPORTUNITIES FOR IMPROVEMENT IN THE PREVENTION AND CARE OF YOUNG ADULT COLORECTAL CANCER.

  • Chelsea Boet,Sarah Debord, Kevin Hays, Kim Newcomer, Susan Pfau, Eric Reddy, Valarie Schlosser, Diana Sloan, Denelle Suranski, Tabitha Trent, Wes Hensel
  • Opening Remarks: Richard R. Barakat, MD, Physician-in-Chief and Director, Northwell Health Cancer Institute
  • How the Survivor Testimonials Framed Today’s Program: Thomas K. Weber, MD, FACS, Northwell Health, Colon Cancer Foundation
  • Housekeeping: Cindy R. Borassi, Colon Cancer Foundation  

8:30 AM – 9:35 AM SESSION I: THE DIMENSIONS OF THE EAO-CRC PROBLEM: TARGET ITEM: ACCURATE, REGULAR, UP TO DATE MEASUREMENT OF KEY METRICS DESCRIBING THE EARLY AGE ONSET COLORECTAL CANCER PUBLIC HEALTH CRISIS.

8:30 AM – 8:40 AM

  • Overview of Global EAO-CRC Incidence Patterns and Trends
    • Thomas K. Weber, MD, FACS, Northwell Health, Colon Cancer Foundation

8:40 AM – 8:50 AM

  • Overview of United States EAO-CRC Incidence Patterns and  Trends
    • Rebecca L. Siegel, MPH, American Cancer Society

8:50 AM – 9:00 AM

  • Utilization of Detailed Centers  for Disease Control (CDC) Cancer Registry Data in the Age of Genomic Medicine
    • Jordan Karlitz, MD, FACG Tulane University School of Medicine  (VIA VIDEO CONFERENCING)

9:00 AM – 9:10 AM

  • Overview of European Cancer Registries Data Resources on EAO-CRC
    • Irit Ben-Aharon, MD, PhD, Rambam Health Care Campus, Haifa, Israel, European Organisation for Research and Treatment of Cancer (EORTC)

9:10 AM – 9:20 AM

  • Survey of Young Onset Patients, Survivors, and Caregivers: Self-Reported Clinical, Psychosocial, Financial and Quality of Life Experiences.
    • Ronit Yarden, Ph.D. MHSA, Colorectal Cancer Alliance

9:20 AM – 9:35 AM

  • Q&A Panel Discussion – Strategic Plan Development

9:35 AM – 9:50 AM

  • Networking, Coffee, Poster Viewing Break

9:50 AM – 11:35 AM  SESSION II: FAMILY HISTORY ASCERTAINMENT IN THE U.S. (ADDRESSING  GAP 1) WHAT STEPS ARE NEEDED TO IMPROVE THE WELL DOCUMENTED LESS THAN OPTIMAL STATUS OF THIS SITUATION? WHAT IS OUR BEST INFORMATION ON THE DOCUMENTATION OF CANCER FAMILY HISTORY IN PRIMARY CARE?  WHAT ARE THE KEY ELEMENTS REQUIRED FOR SUCCESS.

Moderator:  Gregory Feero, MD, PhD, Maine Dartmouth Family Medicine Residency, Augusta, ME; Geisel School of Medicine at Dartmouth, Hanover, NH

9:50 AM – 10:10 AM

  • Electronic Health Records (EHR) and family cancer history ascertainment. The path forward?   
    • Gregory Feero, MD, PhD, Maine Dartmouth Family Medicine Residency, Augusta, ME; Geisel School of Medicine at Dartmouth, Hanover, NH

10:10 AM – 10:25 AM

  • Review of National Colorectal Cancer Roundtable (NCCRT) Family Health History Early Age Onset Colorectal Cancer (EAO-CRC) Task Group Progress  and Overview of the NCCRT Risk Assessment and Screening Toolkit to Detect Familial, Hereditary and Early Onset Colorectal Cancer and next steps for dissemination and implementation
    • Dennis Ahnen, MD, AGAF, FACG, University of Colorado School of Medicine, Gastroenterology of the Rockies

10:25 AM – 10:40 AM

  • Implementation plan for 2018 American Cancer Society recommendations (and rationale) for screening for the early detection of colorectal cancer.
    • Robert A. Smith, PhD, American Cancer Society

10:40 AM – 10:50 AM

  • Strategies for Addressing Early Onset CRC: An NCCRT Report
    • Jan Lowery, Colorado Center for Personalized Medicine

10:50 AM – 11:00 AM

  • Detecting Unaffected Individuals with Lynch Syndrome (DUAL).  
    • Sayoni Lahiri, MS, CGC, UT Southwestern Medical Center

11:00 AM – 11:10 AM

  • Prevalence of Advanced Colorectal Polyps Among First Degree Relatives of EOCRC patients
    • Christine L. Sardo Molmenti, PhD, MPH Feinstein Institute for Medical Research, Northwell Health, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell

11:10 AM – 11:15 AM  

  • Integrating education on the importance of family health history ascertainment and earliest possible diagnosis into the entire continuum of medical and specialty education from medical school through Board Certification, CME and Recertification.
    • Thomas K. Weber, MD, FACS, Northwell Health, Colon Cancer Foundation

11:15 AM – 11:30 AM

  • Q&A Panel Discussion – Strategic Plan Development

11:30 AM – 12:15 PM

LUNCH

12:15 PM – 1:20 PM SESSION III: EARLIEST POSSIBLE DIAGNOSIS AND TREATMENT THROUGH TIMELY RECOGNITION OF THE SYMPTOMS AND SIGNS OF YOUNG ADULT CRC (ADDRESSING GAP 2)

Moderator: Whitney Jones, MD, Clinical Professor of Medicine, University of Louisville

12:15 PM – 12:25 PM

  • A review of the published data documenting delays in diagnosis and the consequences in terms of later stage diagnosis and poorer outcomes
    • Whitney F. Jones, MD, Gastro & Endo Associate

12:25 PM – 12:35 PM

  • Overview of the continuum of providers who interact with patients prior to and up to a diagnosis
    • Chelsea Boet, MD, Spectrum Health Medical Group

12:35 PM – 12:45 PM

  • Lessons Learned: What have we learned from past public health success stories?  
    • Jennifer Brown, PhD, NYC Department of Health & Mental Hygiene

12:45 PM – 12:55 PM

  • Lessons Learned: What have we learned from past public health success stories?  
    • Tony Foleno, Senior Vice President, Strategy & Evaluation, Ad Council; President, Society for Health Communication

12:55 PM – 1:05 PM

  • Introduction of the EAO-CRC National Clinical Alert and Symptoms and Signs Index
    • Andrew Albert, MD, MPH, Chicago Gastro LLC.
    • Erin Peterson, Colon Cancer Coalition
      • Provider Education Outreach Initiatives
      • Patient Awareness and Advocacy Initiatives

1:05 PM – 1:20 PM

  • Q&A Panel Discussion – Strategic Plan Development

1:20 PM – 2:45 PM SESSION IV: TIMELY, EFFECTIVE, QUALITY OF LIFE & FERTILITY PRESERVING STATE OF THE ART TREATMENT (ADDRESSING GAP 3)  

1:20 PM – 1:30 PM

  • Updates on Current Medical Oncology Approaches to Young-Onset CRC
    • Andrea Cercek, MD, Memorial Sloan Kettering Cancer Center

1:30 PM – 1:40 PM

  • Optimal Preservation of Fertility  
    • Nicole Noyes MD, Reproductive Endocrinologist, Northwell Health

1:40 PM – 1:50 PM

  • Novel Approaches to Metastatic Mismatch Repair (MMR) deficient and Microsatellite Stable (MSS) metastatic Colorectal Cancer
    • Cathy Eng, MD, FACP, FASCO, The University of Texas MD Anderson Cancer Center

1:50 PM – 2:00 PM

  • From “Bench to Bedside” CRC Experimental Therapeutics and Phase I & II Trials. What’s New & What’s Next?
    • Wasif M. Saif, MD, MBBS Northwell Health Cancer Institute

2:00 PM – 2:10 PM

  • GAPS in providing Palliative Care and the cost benefit ratio for hospital systems
    • James T. D’Olimpio, MD, FACP, FAAHPM North Shore University Hospital

2:10 PM -2:20 PM

  • Q&A Panel Discussion

2:20 PM – 2:35 PM

  • Identifying the Key Elements of a Center for Early Age Onset Colorectal Cancer – Panel Discussion
    • Eric Reddy, Stage IV Colorectal Cancer Survivor
    • Andrea Cercek, MD, Memorial Sloan Kettering Cancer Center
    • Zana Correa, NP, Memorial Sloan Kettering Cancer Center
    • Kimmie NG, MD, MPH, Dana-Farber Cancer Institute
    • Karen Fasciano, PsyD, Dana-Farber Cancer Institute
    • Christine Louise S. Molmenti, MPH, PhD Feinstein Institute for Medical Research/ Northwell Health
    • Thomas K. Weber, MD, FACS, Northwell Health, Colon Cancer Foundation
    • Krista Nelson, LCSW OSW-C BCD FAOSW, Providence Cancer Institute, Providence St Joseph Health

2:35 PM – 2:45 PM

  • Q&A Panel Discussion – Strategic Plan Development

2:45 PM – 3:00 PM

  • Networking, Coffee, Poster Viewing Break

3:00 PM – 5:35 PM SESSION V: HOW DID THIS HAPPEN? INVESTIGATING THE CAUSES OF EARLY ONSET COLORECTAL CANCERS (EAO-CRC) (ADDRESSING GAP 4)

The Genetics of Heritable CRC: What’s New and Important to Know Regarding the Genetics of EAO-CRC? Moderators: Professors Kauff & Weber

Moderator(s): Noah D. Kauff, MD, Duke Cancer Institute, Duke University Health System and Thomas K. Weber, MD, FACS, Northwell Health, Colon Cancer Foundation

3:00 PM – 3:10 PM

  • Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients with Early-Onset Colorectal Cancer.
    • Heather Hampel, MS, LGC, The Ohio State University Comprehensive Cancer Center

3:10 PM – 3:20 PM

  • Molecular subtype of colorectal cancer associated with early age of onset
    • Xavier Llor, MD, PhD, Yale University School of Medicine Smilow Cancer Center

3:20 PM – 3:30 PM

  • Germline Genetic Variants Associated with Young-Onset Colorectal Cancer: The MSKCC Experience   
    • Zsofia K. Stadler, MD Clinical Director, Clinical Genetics Service, Memorial Sloan Kettering Cancer Center

3:30 PM – 3:40 PM

  • Germline Genetic Features of Young Individuals with Colorectal Cancer
    • Elena M. Stoffel MD MPH, Director Cancer Genetics Clinic, University of Michigan

3:40 PM – 3:50 PM

  • Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer
    • Matthew B. Yurgelun MD, Dana-Farber Cancer Institute, Harvard Medical School

What is driving the increases in EAO-CRC,  80 + % of which is NOT related to the Named Hereditary CRC Syndromes ?   

3:50 PM – 4:00 PM

  • Obesity, Sedentary Behaviors, and Early-Onset CRC,  Yin Cao, MPH, ScD, MPH, Washington University School of Medicine

4:00 PM – 4:10 PM

  • New Suspects: Diet, Microbiome, Immunology and Cancer Risk, Semir Beyaz, PhD, Cold Spring Harbor Laboratories

4:10 PM – 4:20 PM

  • New Research Information: Current Efforts to investigate the causes of increases in MSS CRC among young adults.
    • The United States:
      • Current NCI Funded Investigations into the Causes of Early Age Onset Colorectal Cancer:
          • Colorectal Cancer Risks in People < 50 Years of Age  NIH (RO3): Epidemiology, Richard Hayes, DDS, PhD, MPH, The Cancer Institute at NYU Langone

4:20 PM – 4:30 PM

  • Presentation Early Life Risk Factors and Risk of Colorectal Neoplasia, Kana Wu, MD, PhD, Harvard T.H. Chan School of Public Health, Dana-Farber, Harvard Cancer Center

4:30 PM – 4:40 PM

  • The European Union: Funded Investigations 
    • European Organization for Research and Treatment of Cancer (EORTC): Young Onset CRC: Causation, Treatment and Outcomes, Irit Ben-Aharon, MD, PhD, Rambam Health Care Campus, Haifa, Israel European Organisation for Research and Treatment of Cancer

4:40 PM – 4:50 PM

  • European study of Early-onset Colorectal Cancer (EUREOC): A Collaborative Study of the Biology of Young Onset CRC, Jose Perea, MD, PhD, Fundacion Jimenez Diaz University Hospital, Madrid, Spain

4:50 PM – 5:00 PM

  • In Development: CRAYON: ColoRectal Cancer in Adults at Young ONset: New York City Based Prospective Accrual Study of Young Onset Colorectal Cancer
    • Steven H. Itzkowitz MD, Icahn School of Medicine at Mount Sinai

5:00 PM – 5:10 PM

  • The Beyond CRC Project  
    • Kimmie Ng, MD, MPH, Dana-Farber Cancer Institute

5:10 PM – 5:20 PM

  • The Search for Novel Drivers of Young Onset MSS CRC: An overview of current NIH, CDC and ACS efforts, Thomas K. Weber, MD, FACS, Northwell Health

5:20 PM – 5:30 PM

  • Report back from Denver EAO CRC Research Meeting, Heather Hampel, The Ohio State University Comprehensive Cancer Center

5:30 PM – 5:45 PM

  • Discussion and “Next Steps”

5:45 PM – 6:45 PM

  • Poster Session and Reception

FRIDAY, MAY 3, 2019

8:00 AM – 9:00 AM REGISTRATION AND BREAKFAST WITH THE DOCTORS (Krista Nelson and Karen Fasciano)

9:00 AM – 9:05 AM WELCOME BACK!

Course Co-Director Wasif M. Saif, MD, MBBS, Northwell Health Cancer Institute

9:00 AM – 9:05 AM HOUSEKEEPING

Course Co-Director Susan Peterson, PhD, MPH, The University of Texas MD Anderson Cancer Center

9:05 AM – 10:05 AM

SESSION VI: PALLIATIVE CARE: WHY EARLY IS BEST. (INCLUDING GUIDANCE, SUPPORT AND RESOURCES TO PATIENTS AND CAREGIVERS DURING THEIR TREATMENT JOURNEY/CONTINUUM OF CARE.  (ADDRESSING GAP 5)

James T. D’Olimpio, MD, FACP, FAAHPM North Shore University Hospital

Sarah Debord, Colon Cancer Coalition

Andy Esch, MD, MBA, Palliative Care and Survivorship of Western New York

Karen Fasciano, PsyD, Dana-Farber Cancer Institute

Susan Pfau,

Krista Nelson, LCSW OSW-C BCD FAOSW,

10:05 AM – 10:25 AM

SESSION VI EPIGENETICS AND ITS FUTURE ROLE IN THE DIAGNOSIS AND TREATMENT OF INDIVIDUALS MORE SPECIFICALLY AND ACCURATELY

  1. Richard Boland, MD, AGAF, UC San Diego

10:25 AM – 10:45 AM

  • Networking, Coffee, Poster Viewing Break

10:45 AM – 11:20 PM

STRATEGIC PLANNING SESSION (BREAKOUT GROUPS ACCORDING TO GAP)

  1. Data, accurate, regular to measurement of key metrics
  2. Family History Ascertainment
  3. Earliest Possible Stage Diagnosis
  4. Development of centers of excellence dedicated to the treatment of EAO CRC patients and caregivers
  5. Research into the causes of early onset colorectal cancers

11:20 AM – 11:45 PM

REPORT BACK FROM STRATEGIC ACTION PLAN BREAKOUT GROUPS

THE EAOCRC PLEDGE

11:45 PM – 12:15 PM

ABSTRACT POSTER SESSION AWARDS

CLOSING REMARKS

REGISTER NOW!

REGISTER

2021 SUMMIT SCHEDULE

Friday, May 14, 2021 – 1:00 – 3:00 PM ESTThe Inaugural Status of EAO-CRC in the States Symposium: Solutions for the Struggle
INVITATION ONLY Contact Susan Pistone, pistone@legacy.coloncancerfoundation.org, for more information
Friday, May 14, 2021 – 3:15 – 4:45 PM ESTSESSION I: Improving Earliest Possible Diagnosis and Treatment through Timely Recognition of the Symptoms and Signs of Sporadic Young Adult CRC

Moderator: Whitney Jones, MD, Colon Cancer Prevention Project

– Introduction to the Topic: Whitney Jones, MD
– How will EAO-CRC Incidence and Mortality Rank in 2040? Lola Rahib, PhD, Director of Scientific & Clinical Affairs, Cancer Commons
– How to Involve Primary Care in Improving Earliest Stage Diagnosis: Len Lichtenfeld, MD, MACP, Former Deputy Chief Medical Officer, American Cancer Society; Board of Trustees, CancerCare
– CRC Patient Story: Lisette Caesar, EdD, Founding Principal, Mosaic Preparatory Academy
– Introduction of the Echo Chamber Challenge and Clinical Alert: Erin Peterson, Director of Mission & Partnerships, Colon Cancer Coalition
– Q&A

Friday, May 14, 2021 – 6:00 PM – 7:00 PM EST VIRTUAL: BYOB BLUE COCKTAIL AND NETWORKING EVENT
Friday, May 14, 2021 7:00 – 8:00 PM EST A conversation with digital artist Andre’ Oshea, who was commissioned to create an inspirational tribute piece in memory of actor Chadwick Boseman that will be auctioned. Proceeds from the auction will benefit the Colon Cancer Foundation.
Saturday, May 15, 2021 10:00 AM – 10:10 AM EST

Opening Remarks:
– Susan Wysoki, Interim Executive Director, Paltown Development Foundation
– Shannon Lee-Sin, Stage IIIc Colon Cancer Survivor
Saturday, May 15, 2021 10:10 AM – 10:15 AM ESTWelcome: Zsofia Stadler, MD, Summit Co-Chair; Clinical Director, Clinical Genetics Service, Memorial Sloan Kettering Cancer Center
Saturday, May 15, 2021 10:15 AM – 10:20 AM ESTHousekeeping: Cindy R. Borassi, EAO-CRC Host

Saturday, May 15, 2021 10:20 AM – 10:30 AM ESTFraming the Conversation: Strategic Challenges in Current Medical Care that Contribute to Young Adult Colorectal Cancer (CRC) Incidence and Mortality, Cindy R. Borassi, EAO-CRC Host; President, Colon Cancer Foundation

Saturday, May 15, 2021 10:30 AM – 11:00 AM ESTKEYNOTE: Stephen B. Gruber, MD, PhD, MPH, Vice President, City of Hope National Medical Center

Saturday, May 15, 2021 11:00 AM – 12:15 PM ESTSession II: The Dimensions of the EAO-CRC Problem: Do We Have Accurate, Regular, Up to Date Measurement of Key Metrics Describing the Early Age Onset Colorectal Cancer Public Health Crisis

Moderator: Susan Peterson, PhD, MPH, Co-Chair

-Update on Rising Early-Onset CRC: Impact of Recent Trends on Racial Disparities: Rebecca Siegel, MPH, Scientific Director, Surveillance Research, American Cancer Society
– COVID’s Impact on Cancer Screening – One Year Later: Len Lichtenfeld, MD, MACP, Former Deputy Chief Medical Officer, American Cancer Society; Board of Trustees, CancerCare
– Under 19 EAO-CRC Incidence and Mortality – How Do We Care for Our Youngest Patients? Susan Wysoki, Interim Executive Director, Paltown Development Foundation
– COVID-19 Policy Update – One Year Later: Phylicia L. Woods, JD, MSW, Executive Director, Cancer Policy Institute, Cancer Support Community

Saturday, May 15, 2021 12:15 PM – 1:00 PM EST LIVE LUNCH WITH AN EXPERT BREAKOUT OPTION

1. Hereditary Cancer
a. Robin Dubin, MBA Co-founder/Executive Director, AliveAndKickn
b. Bryson Katona, MD, PhD, Director, Gastrointestinal Cancer Genetics Program and Assistant Professor of Medicine at the Hospital of the University of Pennsylvania
c. Zsofia Stadler, MD, Clinical Director, Clinical Genetics Service, Memorial Sloan Kettering Cancer Center

2. EAO-CRC Patient Advocacy
a. Kim Newcomer, Senior Manager of Medical Advocacy & Community Engagement, Colorectal Cancer Alliance
b. Erin Peterson, Communications Director, Colon Cancer Coalition
c. Terry Wilcox, Executive Director, Patients Rising

3. Medical Oncology – What the Future Holds for Therapies
a. Andrea Cercek, MD, Co-Director Center for Young Onset Colorectal Cancer, Section Head Colorectal Cancer, Associate Attending Memorial Sloan Kettering Cancer Center
b. Marios Giannakis, MD, PhD, Gastrointestinal Cancer Center, Dana-Farber Cancer Institute, Assistant Professor of Medicine, Harvard Medical School

4. Surgical Advances in the Management of Colorectal Cancer
a. Christina E. Bailey, MD, MSCI, Program Director, General Surgery Residency, Assistant Professor of Surgery, Surgical Oncology and Endocrine Surgery, Vanderbilt University School of Medicine
b. Jose’ Perea, MD, PhD. Surgery Department. Fundación Jiménez Díaz University Hospital and Research Institute, Madrid, Spain

5. Epidemiology of EAOCRC: What the BLEEP is Going on?
a. Rebecca Siegel, MPH, Scientific Director, Surveillance Research, American Cancer Society
b. Robert A. Smith, PhD, Senior Vice President, Cancer Screening, American Cancer Society; Adjunct Professor of Epidemiology, Rollins School of Public Health, Emory University School of Medicine

6. Novel Approaches to MMR and MSS Colorectal Cancer
a. Cathy Eng, MD, FACP, Vanderbilt-Ingram Cancer Center, David H. Johnson Chair in Surgical and Medical Oncology Vice-Chair, SWOG GI Committee, Institutional PI, SWOG, Professor of Medicine, Hematology and Oncology, Co-Director, GI Oncology, Co-Leader, Gastrointestinal Cancer Research Program
b. Christopher Lieu, MD, Co-Director of GI Medical Oncology, UCHealth Cancer Care – Anschutz Medical Campus – University of Colorado Cancer Center

7. Psychology of Families Dealing With Cancer – Psychosocial Support Through Treatment
a. Hadley Maya, MSW, LCSW, Center for Young Onset Colorectal Cancer Clinical Social Worker, Memorial Sloan Kettering Cancer Center
b. Susan Peterson, PhD, MPH, Professor of Behavioral Science, Department of Behavioral Science, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center

Saturday, May 15, 2021 1:00 PM – 1:15 PM EST
Networking / Break / Optional Viewing: Colon Cancer Coalition /AliveAndKickn Lynch Video, Colorectal Cancer Alliance Patient Video, or Colon Cancer Foundation – Colon Cancer Prevention Project
Saturday, May 15, 2021 1:15 PM – 2:30 PM EST
SESSION III: Risk Assessment / Family History Ascertainment in the U.S. What Steps are Needed to improve the Well Documented Less Than Optimal Status of this Situation? What is Our Best Information on the Documentation of Cancer Family History in Primary Care? What are the Key Elements Required for Success?

Moderator: Zsofia Stadler, MD, Associate Professor, Clinical Director, Clinical Genetics Service, Memorial Sloan Kettering Cancer Center

1. Screening Guidelines for CRC Screening: What are the Guidelines and How are We Actually Doing?
– CRC Population Screening and Adherence to Recommendations: David Greenwald, MD, Director Of Clinical Gastroenterology and Endoscopy, The Mount Sinai Hospital
– Surveillance in High-risk Patients (Advanced Adenomas, Genetic Susceptibility): Bryson Katona, MD, PhD, Director, Gastrointestinal Cancer Genetics Program; Assistant Professor of Medicine at The Hospital of The University Of Pennsylvania

2. Increasing Access to Genetic Testing: What do We Need to do to Improve the Situation?
– How to Increase Access to Genetic Testing for Lynch Syndrome: Robin Dubin, MBA, Co-founder/Executive Director, AliveAndKickn
– Facilitative Genetic Testing: Melissa Frey, MD, Assistant Professor Of Obstetrics and Gynecology, Weill Cornell Medical College
– Action at the State Level: The Role of HCRA, Call to Action for EHRs and Genetic Testing Companies: Whitney Jones, MD, Colon Cancer Prevention Project

Saturday, May 15, 2021 2:30 PM – 2:45 PM EST Q & A, Action Plan Consensus Building – Wrap Up
Sunday, May 16, 2021 10:00 AM – 10:30 AM EST Welcome: Jordan J. Karlitz, MD, Chief Medical Officer, Director of Clinical Operations at Gastro Girl and GI OnDemand Virtual Care and Telehealth Platform
Sunday, May 16, 2021 10:30 AM – 12:30 PM EST SESSION IV: How to Provide Timely, Effective, Quality of Life & Fertility Preserving Treatment: What Are Key Elements of Coordinated Care for Early Onset Colorectal Cancer?

Moderators:
– Andrea Cercek, MD, Co-Director Center for Young Onset Colorectal Cancer, Section Head Colorectal Cancer, Associate Attending Memorial Sloan Kettering Cancer Center
– Case History Presented by: Yi-Qian Nancy You, MD, MHSc, FACS, Department of Surgical Oncology, Division of Surgery, The University of Texas MD Anderson Cancer Center

Presenters:
– Patient Perspective: Manju George, MVSc, PhD, Scientific Director, Paltown Development Foundation
– Nurse Navigation: Amy Hayes, BSN, RN, OCN, Nurse Navigator, Vanderbilt-Ingram Cancer Center
– Genetics: Zsofia Stadler, MD, Associate Professor, Clinical Director, Clinical Genetics Service, Memorial Sloan Kettering Cancer Center
– Medical Oncology and New Therapeutics: Cathy Eng, MD, Vanderbilt-Ingram Cancer Center,
– Radiation Oncology: Harvey Mamon, MD, PhD, Associate Professor, Radiation Oncology, Harvard Medical School, Director of GI Radiation Oncology, Brigham And Women’s Hospital, Chief, Division of Gastrointestinal Radiation Oncology
– Surgery: Kellie L. Mathis, MD, Mayo Clinic
– Financial Burden/Toxicity: Hadley Maya, MSW, LCSW, Center for Young Onset Colorectal Cancer, Memorial Sloan Kettering Cancer Center
– Psychosocial Needs: Krista Nelson, LCSW OSW-C BCD FAOS, President of the Association of Community Cancer Centers
– Pediatrics: Michael Roth, MD, Associate Professor of Pediatrics, The University of Texas MD Anderson Cancer Center; Chair, AYA Oncology Discipline Committee, Children’s Oncology Group
– Fertility Preservation, Terri L. Woodard, MD, Associate Professor Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center
– Palliative Care: Janet L. Abrahm, MD, Former Chief, Division of Adult Palliative Care, Department of Psychosocial Oncology and Palliative Care, Dana-Farber Cancer Institute and Brigham and Women’s Hospital; Professor of Medicine, Harvard Medical School

– Q&A

Sunday, May 16, 2021 12:30 PM – 1:00 PM EST Networking / Break / Optional Viewing
Sunday, May 16, 2021 1:00 PM – 2:00 PM EST Breakout Options

1. Understanding and Addressing Disparities in Early-Age Onset Colorectal Cancer
Moderator: Candace Henley, Chief Surviving Officer, The Blue Hat Foundation
– Introduction, Candace Henley, Chief Surviving Officer, The Blue Hat Foundation
– Overview of Findings: Disparities in Early-Onset Colorectal Cancer
a. Elena M. Stoffel, MD, MPH, Director of the University of Michigan Cancer Genetics Clinic; Assistant Professor of Internal Medicine, University of Michigan
b. Sonia Kupfer, MD, Associate Professor of Medicine, Director, Gastrointestinal Cancer Risk and Prevention Clinic, Co-Director, Comprehensive Cancer Risk and Prevention Clinic, CRC Patient and CRC Community Organizer/Advocate, University of Chicago
– Patient/Caregiver Perspective
a. Angela Caraway, MMP, President, TCMG Inc; Patient Advocate
b. Jasmin Mejia, Member Services and Events Manager, Urban Collaborative at Arizona State University; Chair, Arizona Allies; Volunteer, Arizona Allies – Colorectal Cancer Alliance
– Q&A

2. Integrating Music Therapy in Cancer
Moderator: Cindy R. Borassi, President, The Colon Cancer Foundation
a. Joanne V. Loewy DA, LCAT, MT-BC, The Louis Armstrong Center for Music and Medicine, Icahn School of Medicine, Mount Sinai Hospital
b. Manjeet Chadha, MD, MHA, FACR, FASTR, Department of Radiation Oncology, Icahn School of Medicine, Mount Sinai Hospital
c. Andrew Rossetti, MMT, LCAT, MT-BC, The Louis Armstrong Center for Music and Medicine, Department of Radiation Oncology, Mount Sinai Hospital
– Q&A

Sunday, May 16, 2021 2:25 PM – 3:30 PM EST SESSION V: How Did This Happen? Investigating the Causes of Early Onset Colorectal Cancers (EAO-CRC)

Moderator: Stephen B. Gruber, MD, PhD, MPH, Vice President, City of Hope National Medical Center

Panel Discussion: Everyone addresses the Future Direction – What Still Needs to be Done? Challenge: Where are we Headed and How do We Solve This – Think Outside the Box.

– Mining Electronic Health Record Data and Integration With Large-scale Genomic Analyses: Is This Where We are Going? Francisco Sanchez-Vega, PhD, Assistant Attending Computational Oncologist, Colorectal Cancer Service of the Department of Surgery, Memorial Sloan Kettering Cancer Center
– The Colorectal Cancer Pooling Project: What Can We Learn From this International Resource? Peter Campbell, PhD, Scientific Director, Epidemiology Research, American Cancer Society
– The BEYOND CRC Project: Better Understanding of Young-Onset Colorectal Cancer: Kimmie Ng, MD, MPH, Associate Professor of Medicine at Harvard Medical School, Founding Director of the Young-Onset Colorectal Cancer Center and Director of Clinical and Biospecimen Research in the Center for Gastrointestinal Oncology at Dana-Farber Cancer Institute
– How are Microbiome Interactions Contributing to the Rise of EAO-CRC? Cynthia Sears, MD, Professor, Johns Hopkins University School of Medicine
– Earlier Life Exposures: Maternal Obesity and Gestational Growth: Caitlin Murphy, PhD, Assistant Professor, Department of Population and Data Sciences. UT Southwestern
– Genomics – The European Perspective: José Perea MD, PhD, Surgery Department, Fundación Jiménez Díaz University Hospital and Research Institute, Madrid, Spain
– “DEMETRA”: Diet obEsity sMoking Epigenetics geneTics biomaRkers physical Activity: Giulia Martina Cavestro, MD, PhD, Director of the Postgraduate School of Gastroenterology, Gastroenterology and Gastrointestinal Endoscopy Unit, Vita-Salute San Raffaele University, San Raffaele Scientific Institute, Milan

– Q&A

Sunday, May 16, 2021 3:30 – 3:40 PM EST RECAP / NEXT STEPS

Have you joined the place to be to talk about EAO-CRC? CRCCONNECT.ORG?

SUMMIT CO-DIRECTORS

Jordan Karlitz,MD

SUMMIT CO-CHAIR

Assistant Clinical Professor of Medicine and Director, GI Hereditary Cancer and Genetics Program at Tulane

Susan K. Peterson, PhD, MPH

SUMMIT CO-CHAIR / ABSTRACT CHAIR

Department of Behavioral Science, Division of Cancer Prevention and Population Sciences

Zsofia Stadler, MD

SUMMIT CO-CHAIR

Clinical Laboratory Investigator, The Kenneth Offit Laboratory, Memorial Sloan Kettering Cancer Center

Yi-Qian Nancy You, MD, MHSc, FACS

SUMMIT CO-CHAIR

Department of Surgical Oncology, Division of Surgery, MD Anderson Cancer Center

COURSE PLANNING COMMITTEE

April Barry, LSW, MSW

Planning Committee Member

Performance, Improvement & Evaluation Manager
Pennsylvania Department of Health

Cindy R. Borassi

Planning Committee Member

President, Colon Cancer Foundation

Andrea Cercek, MD

Planning Committee Member

Memorial Sloan Kettering Cancer Center

Surabhi Dangi-Garimella, PhD

Planning Committee Member

Scientific Director
Colon Cancer Foundation

Whitney Jones, MD

Planning Committee Member

Founder, Colon Cancer Prevention Project

Kimmie Ng, MD

Planning Committee Member

Founding Director of the Young-Onset Colorectal Cancer Center, and Director of Clinical and Biospecimen Research in the Center for Gastrointestinal Oncology

Dr. José Perea MD, PhD

Planning Committee Member

Surgery Department. Fundación Jiménez Díaz University Hospital and Research Institute. Madrid, SPAIN.

Erin Peterson

Planning Committee Member

Director of Mission and Partnerships
Colon Cancer Coalition

EAO-CRC SUMMIT™ OBJECTIVES

This event will bring together leading clinicians, scientists as well as early age onset (EAO) colorectal cancer (CRC) survivors and caregivers from across the country and internationally. The program will provide extensive opportunities for participants to advance their understanding of the rapidly increasing incidence of rectal and colon cancer among young adults under 50 years of age in the U.S. and abroad.

This groundbreaking program will, for a sixth consecutive year, provide all participants the opportunity to hear and question leading clinicians and researchers on the lifesaving potential of timely clinical risk assessment / family cancer health history; earliest possible stage diagnosis, optimal, fertility preserving clinical care, as well as the latest information regarding national and international EAO CRC incidence trends, pathogenesis, and genetics. In addition, this year’s program will present a “Research in Progress” segment providing an update on currently NCI funded and planned EAO CRC research projects from across America and Europe.

Again this year, important Keynote Sessions based on needs-assessments from our survivor community will address challenging issues such as EAO-CRC Focused Survivorship Programs: How Are They Measuring Up?, specifically requested by our Young Adult CRC Survivor Program Advisory Group.

The EAO-CRC SUMMIT™ will include lectures, optional working groups and panel discussions designed to advance the “state-of-the-science” addressing EAO-CRC. Our faculty will once again be world class speakers representing leading academic medical centers with major additional inspiring programmatic contributions from the Early Age Onset Colorectal Cancer Survivor Community of the United States and beyond.

EAO-CRC SUMMIT™ EDUCATIONAL OBJECTIVES

  • Provide an expert review of the latest published information on the increasing incidence and mortality associated with Early Age Onset Colorectal Cancer in the United States and around the globe
  • Provide an evidence-based framework for reducing risk, increasing early stage diagnosis and improving treatment and outcomes for young adult colorectal cancer patients.
  • Review the State-of-the-Science regarding the known and possible causes of the increasing incidence of EAO-CRC including alterations in our food and water supply, the contribution of novel germline genetic factors and etiologic clues based on the molecular biology of EAO-CRC cancers.
  • Define the “Gaps” in our current understanding of Early Age Onset Colorectal Cancer in order to set our clinical and research priorities and develop a strategic plan to reduce EAO-CRC incidence and mortality.

SPONSORSHIP OPPORTUNITIES

The sponsors of the EAO-CRC Summit make it possible for us to build public awareness of colorectal cancer (CRC) including hereditary colorectal cancer and the importance of timely screening and prevention.  Their support also allows us to help sponsor prevention programs in New York City including screening efforts for the uninsured and innovative translational research projects focused on early age onset of colorectal cancer.

As a sponsor of the Summit you have the opportunity to reach thousands who join us each year to raise awareness of this deadly and yet preventable disease.

If you are interested in joining our community of Sponsors, please contact Sandra Vassos at 914.305.6674.

PLANNED PRESENTATIONS AND INVITED FACULTY INCLUDE

CRC 2019 BROCHURE

THURSDAY, MAY 2, 2019

7:00 AM – 8:00 AM REGISTRATION AND BREAKFAST

8:00 AM – 8:30 AM FRAMING THE CONVERSATION: STRATEGIC CHALLENGES IN CURRENT MEDICAL CARE THAT CONTRIBUTE TO YOUNG ADULT COLORECTAL CANCER (CRC) INCIDENCE AND MORTALITY. SURVIVOR TESTIMONIALS UNDERSCORE OPPORTUNITIES FOR IMPROVEMENT IN THE PREVENTION AND CARE OF YOUNG ADULT COLORECTAL CANCER.

  • Chelsea Boet,Sarah Debord, Kevin Hays, Kim Newcomer, Susan Pfau, Eric Reddy, Valarie Schlosser, Diana Sloan, Denelle Suranski, Tabitha Trent, Wes Hensel
  • Opening Remarks: Richard R. Barakat, MD, Physician-in-Chief and Director, Northwell Health Cancer Institute
  • How the Survivor Testimonials Framed Today’s Program: Thomas K. Weber, MD, FACS, Northwell Health, Colon Cancer Foundation
  • Housekeeping: Cindy R. Borassi, Colon Cancer Foundation  

8:30 AM – 9:35 AM SESSION I: THE DIMENSIONS OF THE EAO-CRC PROBLEM: TARGET ITEM: ACCURATE, REGULAR, UP TO DATE MEASUREMENT OF KEY METRICS DESCRIBING THE EARLY AGE ONSET COLORECTAL CANCER PUBLIC HEALTH CRISIS.

8:30 AM – 8:40 AM

  • Overview of Global EAO-CRC Incidence Patterns and Trends
    • Thomas K. Weber, MD, FACS, Northwell Health, Colon Cancer Foundation

8:40 AM – 8:50 AM

  • Overview of United States EAO-CRC Incidence Patterns and  Trends
    • Rebecca L. Siegel, MPH, American Cancer Society

8:50 AM – 9:00 AM

  • Utilization of Detailed Centers  for Disease Control (CDC) Cancer Registry Data in the Age of Genomic Medicine
    • Jordan Karlitz, MD, FACG Tulane University School of Medicine  (VIA VIDEO CONFERENCING)

9:00 AM – 9:10 AM

  • Overview of European Cancer Registries Data Resources on EAO-CRC
    • Irit Ben-Aharon, MD, PhD, Rambam Health Care Campus, Haifa, Israel, European Organisation for Research and Treatment of Cancer (EORTC)

9:10 AM – 9:20 AM

  • Survey of Young Onset Patients, Survivors, and Caregivers: Self-Reported Clinical, Psychosocial, Financial and Quality of Life Experiences.
    • Ronit Yarden, Ph.D. MHSA, Colorectal Cancer Alliance

9:20 AM – 9:35 AM

  • Q&A Panel Discussion – Strategic Plan Development

9:35 AM – 9:50 AM

  • Networking, Coffee, Poster Viewing Break

9:50 AM – 11:35 AM  SESSION II: FAMILY HISTORY ASCERTAINMENT IN THE U.S. (ADDRESSING  GAP 1) WHAT STEPS ARE NEEDED TO IMPROVE THE WELL DOCUMENTED LESS THAN OPTIMAL STATUS OF THIS SITUATION? WHAT IS OUR BEST INFORMATION ON THE DOCUMENTATION OF CANCER FAMILY HISTORY IN PRIMARY CARE?  WHAT ARE THE KEY ELEMENTS REQUIRED FOR SUCCESS.

Moderator:  Gregory Feero, MD, PhD, Maine Dartmouth Family Medicine Residency, Augusta, ME; Geisel School of Medicine at Dartmouth, Hanover, NH

9:50 AM – 10:10 AM

  • Electronic Health Records (EHR) and family cancer history ascertainment. The path forward?   
    • Gregory Feero, MD, PhD, Maine Dartmouth Family Medicine Residency, Augusta, ME; Geisel School of Medicine at Dartmouth, Hanover, NH

10:10 AM – 10:25 AM

  • Review of National Colorectal Cancer Roundtable (NCCRT) Family Health History Early Age Onset Colorectal Cancer (EAO-CRC) Task Group Progress  and Overview of the NCCRT Risk Assessment and Screening Toolkit to Detect Familial, Hereditary and Early Onset Colorectal Cancer and next steps for dissemination and implementation
    • Dennis Ahnen, MD, AGAF, FACG, University of Colorado School of Medicine, Gastroenterology of the Rockies

10:25 AM – 10:40 AM

  • Implementation plan for 2018 American Cancer Society recommendations (and rationale) for screening for the early detection of colorectal cancer.
    • Robert A. Smith, PhD, American Cancer Society

10:40 AM – 10:50 AM

  • Strategies for Addressing Early Onset CRC: An NCCRT Report
    • Jan Lowery, Colorado Center for Personalized Medicine

10:50 AM – 11:00 AM

  • Detecting Unaffected Individuals with Lynch Syndrome (DUAL).  
    • Sayoni Lahiri, MS, CGC, UT Southwestern Medical Center

11:00 AM – 11:10 AM

  • Prevalence of Advanced Colorectal Polyps Among First Degree Relatives of EOCRC patients
    • Christine L. Sardo Molmenti, PhD, MPH Feinstein Institute for Medical Research, Northwell Health, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell

11:10 AM – 11:15 AM  

  • Integrating education on the importance of family health history ascertainment and earliest possible diagnosis into the entire continuum of medical and specialty education from medical school through Board Certification, CME and Recertification.
    • Thomas K. Weber, MD, FACS, Northwell Health, Colon Cancer Foundation

11:15 AM – 11:30 AM

  • Q&A Panel Discussion – Strategic Plan Development

11:30 AM – 12:15 PM

LUNCH

12:15 PM – 1:20 PM SESSION III: EARLIEST POSSIBLE DIAGNOSIS AND TREATMENT THROUGH TIMELY RECOGNITION OF THE SYMPTOMS AND SIGNS OF YOUNG ADULT CRC (ADDRESSING GAP 2)

Moderator: Whitney Jones, MD, Clinical Professor of Medicine, University of Louisville

12:15 PM – 12:25 PM

  • A review of the published data documenting delays in diagnosis and the consequences in terms of later stage diagnosis and poorer outcomes
    • Whitney F. Jones, MD, Gastro & Endo Associate

12:25 PM – 12:35 PM

  • Overview of the continuum of providers who interact with patients prior to and up to a diagnosis
    • Chelsea Boet, MD, Spectrum Health Medical Group

12:35 PM – 12:45 PM

  • Lessons Learned: What have we learned from past public health success stories?  
    • Jennifer Brown, PhD, NYC Department of Health & Mental Hygiene

12:45 PM – 12:55 PM

  • Lessons Learned: What have we learned from past public health success stories?  
    • Tony Foleno, Senior Vice President, Strategy & Evaluation, Ad Council; President, Society for Health Communication

12:55 PM – 1:05 PM

  • Introduction of the EAO-CRC National Clinical Alert and Symptoms and Signs Index
    • Andrew Albert, MD, MPH, Chicago Gastro LLC.
    • Erin Peterson, Colon Cancer Coalition
      • Provider Education Outreach Initiatives
      • Patient Awareness and Advocacy Initiatives

1:05 PM – 1:20 PM

  • Q&A Panel Discussion – Strategic Plan Development

1:20 PM – 2:45 PM SESSION IV: TIMELY, EFFECTIVE, QUALITY OF LIFE & FERTILITY PRESERVING STATE OF THE ART TREATMENT (ADDRESSING GAP 3)  

1:20 PM – 1:30 PM

  • Updates on Current Medical Oncology Approaches to Young-Onset CRC
    • Andrea Cercek, MD, Memorial Sloan Kettering Cancer Center

1:30 PM – 1:40 PM

  • Optimal Preservation of Fertility  
    • Nicole Noyes MD, Reproductive Endocrinologist, Northwell Health

1:40 PM – 1:50 PM

  • Novel Approaches to Metastatic Mismatch Repair (MMR) deficient and Microsatellite Stable (MSS) metastatic Colorectal Cancer
    • Cathy Eng, MD, FACP, FASCO, The University of Texas MD Anderson Cancer Center

1:50 PM – 2:00 PM

  • From “Bench to Bedside” CRC Experimental Therapeutics and Phase I & II Trials. What’s New & What’s Next?
    • Wasif M. Saif, MD, MBBS Northwell Health Cancer Institute

2:00 PM – 2:10 PM

  • GAPS in providing Palliative Care and the cost benefit ratio for hospital systems
    • James T. D’Olimpio, MD, FACP, FAAHPM North Shore University Hospital

2:10 PM -2:20 PM

  • Q&A Panel Discussion

2:20 PM – 2:35 PM

  • Identifying the Key Elements of a Center for Early Age Onset Colorectal Cancer – Panel Discussion
    • Eric Reddy, Stage IV Colorectal Cancer Survivor
    • Andrea Cercek, MD, Memorial Sloan Kettering Cancer Center
    • Zana Correa, NP, Memorial Sloan Kettering Cancer Center
    • Kimmie NG, MD, MPH, Dana-Farber Cancer Institute
    • Karen Fasciano, PsyD, Dana-Farber Cancer Institute
    • Christine Louise S. Molmenti, MPH, PhD Feinstein Institute for Medical Research/ Northwell Health
    • Thomas K. Weber, MD, FACS, Northwell Health, Colon Cancer Foundation
    • Krista Nelson, LCSW OSW-C BCD FAOSW, Providence Cancer Institute, Providence St Joseph Health

2:35 PM – 2:45 PM

  • Q&A Panel Discussion – Strategic Plan Development

2:45 PM – 3:00 PM

  • Networking, Coffee, Poster Viewing Break

3:00 PM – 5:35 PM SESSION V: HOW DID THIS HAPPEN? INVESTIGATING THE CAUSES OF EARLY ONSET COLORECTAL CANCERS (EAO-CRC) (ADDRESSING GAP 4)

The Genetics of Heritable CRC: What’s New and Important to Know Regarding the Genetics of EAO-CRC? Moderators: Professors Kauff & Weber

Moderator(s): Noah D. Kauff, MD, Duke Cancer Institute, Duke University Health System and Thomas K. Weber, MD, FACS, Northwell Health, Colon Cancer Foundation

3:00 PM – 3:10 PM

  • Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients with Early-Onset Colorectal Cancer.
    • Heather Hampel, MS, LGC, The Ohio State University Comprehensive Cancer Center

3:10 PM – 3:20 PM

  • Molecular subtype of colorectal cancer associated with early age of onset
    • Xavier Llor, MD, PhD, Yale University School of Medicine Smilow Cancer Center

3:20 PM – 3:30 PM

  • Germline Genetic Variants Associated with Young-Onset Colorectal Cancer: The MSKCC Experience   
    • Zsofia K. Stadler, MD Clinical Director, Clinical Genetics Service, Memorial Sloan Kettering Cancer Center

3:30 PM – 3:40 PM

  • Germline Genetic Features of Young Individuals with Colorectal Cancer
    • Elena M. Stoffel MD MPH, Director Cancer Genetics Clinic, University of Michigan

3:40 PM – 3:50 PM

  • Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer
    • Matthew B. Yurgelun MD, Dana-Farber Cancer Institute, Harvard Medical School

What is driving the increases in EAO-CRC,  80 + % of which is NOT related to the Named Hereditary CRC Syndromes ?   

3:50 PM – 4:00 PM

  • Obesity, Sedentary Behaviors, and Early-Onset CRC,  Yin Cao, MPH, ScD, MPH, Washington University School of Medicine

4:00 PM – 4:10 PM

  • New Suspects: Diet, Microbiome, Immunology and Cancer Risk, Semir Beyaz, PhD, Cold Spring Harbor Laboratories

4:10 PM – 4:20 PM

  • New Research Information: Current Efforts to investigate the causes of increases in MSS CRC among young adults.
    • The United States:
      • Current NCI Funded Investigations into the Causes of Early Age Onset Colorectal Cancer:
          • Colorectal Cancer Risks in People < 50 Years of Age  NIH (RO3): Epidemiology, Richard Hayes, DDS, PhD, MPH, The Cancer Institute at NYU Langone

4:20 PM – 4:30 PM

  • Presentation Early Life Risk Factors and Risk of Colorectal Neoplasia, Kana Wu, MD, PhD, Harvard T.H. Chan School of Public Health, Dana-Farber, Harvard Cancer Center

4:30 PM – 4:40 PM

  • The European Union: Funded Investigations 
    • European Organization for Research and Treatment of Cancer (EORTC): Young Onset CRC: Causation, Treatment and Outcomes, Irit Ben-Aharon, MD, PhD, Rambam Health Care Campus, Haifa, Israel European Organisation for Research and Treatment of Cancer

4:40 PM – 4:50 PM

  • European study of Early-onset Colorectal Cancer (EUREOC): A Collaborative Study of the Biology of Young Onset CRC, Jose Perea, MD, PhD, Fundacion Jimenez Diaz University Hospital, Madrid, Spain

4:50 PM – 5:00 PM

  • In Development: CRAYON: ColoRectal Cancer in Adults at Young ONset: New York City Based Prospective Accrual Study of Young Onset Colorectal Cancer
    • Steven H. Itzkowitz MD, Icahn School of Medicine at Mount Sinai

5:00 PM – 5:10 PM

  • The Beyond CRC Project  
    • Kimmie Ng, MD, MPH, Dana-Farber Cancer Institute

5:10 PM – 5:20 PM

  • The Search for Novel Drivers of Young Onset MSS CRC: An overview of current NIH, CDC and ACS efforts, Thomas K. Weber, MD, FACS, Northwell Health

5:20 PM – 5:30 PM

  • Report back from Denver EAO CRC Research Meeting, Heather Hampel, The Ohio State University Comprehensive Cancer Center

5:30 PM – 5:45 PM

  • Discussion and “Next Steps”

5:45 PM – 6:45 PM

  • Poster Session and Reception

FRIDAY, MAY 3, 2019

8:00 AM – 9:00 AM REGISTRATION AND BREAKFAST WITH THE DOCTORS (Krista Nelson and Karen Fasciano)

9:00 AM – 9:05 AM WELCOME BACK!

Course Co-Director Wasif M. Saif, MD, MBBS, Northwell Health Cancer Institute

9:00 AM – 9:05 AM HOUSEKEEPING

Course Co-Director Susan Peterson, PhD, MPH, The University of Texas MD Anderson Cancer Center

9:05 AM – 10:05 AM

SESSION VI: PALLIATIVE CARE: WHY EARLY IS BEST. (INCLUDING GUIDANCE, SUPPORT AND RESOURCES TO PATIENTS AND CAREGIVERS DURING THEIR TREATMENT JOURNEY/CONTINUUM OF CARE.  (ADDRESSING GAP 5)

James T. D’Olimpio, MD, FACP, FAAHPM North Shore University Hospital

Sarah Debord, Colon Cancer Coalition

Andy Esch, MD, MBA, Palliative Care and Survivorship of Western New York

Karen Fasciano, PsyD, Dana-Farber Cancer Institute

Susan Pfau,

Krista Nelson, LCSW OSW-C BCD FAOSW,

10:05 AM – 10:25 AM

SESSION VI EPIGENETICS AND ITS FUTURE ROLE IN THE DIAGNOSIS AND TREATMENT OF INDIVIDUALS MORE SPECIFICALLY AND ACCURATELY

  1. Richard Boland, MD, AGAF, UC San Diego

10:25 AM – 10:45 AM

  • Networking, Coffee, Poster Viewing Break

10:45 AM – 11:20 PM

STRATEGIC PLANNING SESSION (BREAKOUT GROUPS ACCORDING TO GAP)

  1. Data, accurate, regular to measurement of key metrics
  2. Family History Ascertainment
  3. Earliest Possible Stage Diagnosis
  4. Development of centers of excellence dedicated to the treatment of EAO CRC patients and caregivers
  5. Research into the causes of early onset colorectal cancers

11:20 AM – 11:45 PM

REPORT BACK FROM STRATEGIC ACTION PLAN BREAKOUT GROUPS

THE EAOCRC PLEDGE

11:45 PM – 12:15 PM

ABSTRACT POSTER SESSION AWARDS

CLOSING REMARKS

INVITED FACULTY

This year the Summit will feature presentations from EAO-CRC survivors, caregivers clinicians from the nation’s leading cancer centers, and representatives of CRC advocacy organizations including 
AliveAndKickn
American Cancer Society
Association of Community Cancer Centers
Brigham and Women’s Hospital
Cancer Policy Institute at Cancer Support Community
Chicago Gastro LLC.
City of Hope National Medical Center
Colontown
Colorectal Cancer Alliance
Colon Cancer Coalition
Colon Cancer Prevention Project
Dana-Farber Cancer Institute
Duke Divinity School
Fundacion Jimenez Diaz University Hospital and Research Institute, Madrid
Harvard Medical School
Dartmouth Geisel School of Medicine
Harvard T.H. Chan School of Public Health
The Kenneth Offit Lab
Hospital of the University of Pennsylvania
Icahn School of Medicine at Mt. Sinai Hospital
Johns Hopkins University School of Medicine
MD Anderson Cancer Center
Memorial Sloan Kettering Cancer Center
Mount Sinai Beth Israel
The Mount Sinai Medical Hospital
Mosaic Preparatory Academy

National Colorectal Cancer Roundtable (NCCRT)
the Never Too Young Coalition
New York-Presbyterian/Herbert Irving Comprehensive Cancer Center
Patients Rising
Palliative Care and Survivorship of Western New York Pennsylvania Department of Health
Providence Cancer Institute
School of Gastroenterology, Gastroenterology and Gastrointestinal Endoscopy Unit, Vita-Salute San Raffaele University, San Raffaele Scientific Institute, Milan
The Caraway Group
Tulane University School of Medicine
UC Health Cancer Care – Anshutz Medical Campus – University of Colorado Cancer Center
Vanderbilt-Ingram Cancer Center
Weil Cornell Medical College
Janet L. Abrahm, MDDana-Farber Cancer Institute and Brigham and Women’s Hospital, Harvard Medical School
Christina E. Bailey, MD, MSCIVanderbilt University School of Medicine
April Barry, LSW, MSWPennsylvania Department of Health
Kate Bowler, PhD Duke Divinity School
Lisette Caesar, EdD
Mosaic Preparatory Academy
Peter Campbell, PhD American Cancer Society
Angela Caraway, MMP TCMG Inc
Giulia Martina Cavestro, MD, PhDSchool of Gastroenterology, Gastroenterology and Gastrointestinal Endoscopy Unit, Vita-Salute San Raffaele University, San Raffaele Scientific Institute, Milan
Andrea Cercek, MD
Memorial Sloan Kettering Cancer Center
Manjeet Chadha, MD, MHA, FACR, FASTRODepartment of Radiation Oncology, Icahn School of Medicine, Mount Sinai Hospital
Robin Dubin, MBA AliveAndKickn
Cathy Eng, MD, FACP, FASCO
Vanderbilt-Ingram Cancer Center
Melissa Frey, MDWeill-Cornell Medical College
Manju George, MVSc, PhDPaltown Development Foundation
Marios Giannakis, MD, PhD

Dana-Farber Cancer Institute, Harvard Medical School
David Greenwald, MDThe Mount Sinai Hospital, Albert Einstein College of Medicine
Steven Gruber, MD, PhD, MPHCity of Hope National Medical Center
Amy Hayes, BSD, RN, OCNVanderbilt-Ingram Cancer Center
Candace Henley The Blue Hat Foundation
Whitney Jones MDMidwest Gastroenterology Associates, Colon Cancer Prevention Project

Jordan Karlitz, MD, FACG
Tulane University School of Medicine
Bryson Katona, MD, PhDUniversity of Pennsylvania
Sonia Kupfer, MDUniversity of Chicago
Leonard Lichtenfeld, MD, MACPCancer Care
Shannon Lee-SinStage IIIc Colon Cancer Survivor
Christopher Lieu, MDUC Health Center, Anshutz Medical Campus, University of Colorado Cancer Center
Joanne V. Loewy, DA, LCAT, MT-BCThe Louis Armstrong Center for Music and Medicine, Icahn School of Medicine, Mount Sinai Hospital
Harvey Mamon, MD, PhD Harvard Medical School, Brigham and Women’s Hospital
Kellie L. Mathis, MDMayo Clinic
Hadley Maya, MSW, LCSWMemorial Sloan Kettering Cancer Center
Jasmin Mejia Arizona State University, Arizona Allies, Colorectal Cancer Alliance
Caitlin Murphy, PhD, MPHUT Southwestern
Krista Nelson, LCSW, OSW-C, BCD, FAOSWProvidence Cancer Institute, Association of Community Cancer Centers
Kimmie Ng, MD, MPHHarvard Medical School, Dana-Farber Cancer Institute
Jose’ Perea, MD, PhDFundacion Jimenez Diaz University Hospital
Erin Peterson
Colon Cancer Coalition
Susan Peterson PhD, MPH Department of Behavioral Science, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center
Andrew Rossetti, MMT, LCAT, MT-BCThe Louis Armstrong Center for Music and Medicine, Department of Radiation Oncology, Mount Sinai Hospital
Michael Roth, MDThe University of Texas MD Anderson Cancer Center
Francisco Sanchez-Vega, PhD, Colorectal Cancer Service of the Department of Surgery, Memorial Sloan Kettering Cancer Center
Cynthia Sears, MD Johns Hopkins University School of Medicine
Rebecca L. Siegel, MPHAmerican Cancer Society
Robert A. Smith, PhDAmerican Cancer Society, Emory University School of Medicine
Zsofia Stadler, MDMemorial Sloan Kettering Cancer Center, The Kenneth Offit Lab
Elena M. Stoffel, MD, MPHUniversity of Michigan
Terry WilcoxPatients Rising
Phylicia L. Woods, JD, MSWCancer Policy Insitute, Cancer Support Community
Susan Wysoki, WHNP, FAANPColontown; Paltown Development Foundation
Terri L. Woodard, MDThe University of Texas MD Anderson Cancer Center
Yi-Qian Nancy You, MD, MHSc, FACSThe University of Texas MD Anderson Cancer Center

CME INFORMATION

RMCHCS designates this live activity for a maximum of 12 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

ABIM MOC Statement: Successful completion of this CME activity enables the participant to earn up to 10.5 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC points.

Accreditation Statement: This activity has been planned and implemented in accordance with the accreditation requirements and policies of the New Mexico Medical Society (NMMS) through the joint providership of Rehoboth McKinley Christian Health Care Services (RMCHCS) and the Colon Cancer Foundation. RMCHCS is accredited by the NMMS to provide continuing medical education for physicians.

ABSTRACTS & SCHOLARSHIPS

The EAO-CRC Program Planning Committee invites attendees to submit abstracts for a poster presentation at the seventh annual meeting on May 11-12, 2021.  Abstracts may describe research or programs, and may have been presented elsewhere.

KEY DATES

Deadline for submission is January 15, 2021. Abstracts should be submitted as an MS Word document to the following email address:  abstracts@legacy.coloncancerfoundation.org.

January 15, 2021 at 11:59 PM ET
Abstract Submission Deadline

TBD

Early Bird Registration Deadline

TBD

Hotel Reservation Deadline

TBD

Abstract Approval Letters Disseminated

TBD

Abstracts Released on EAO-CRC Meeting Library

May 11 7:00 AM – 9:00 PM, May 12 7:00 AM – 12:00 PM

7th Annual EAO-CRC Summit

ABSTRACT SUBMISSION GUIDELINES

Abstracts should be submitted as an MS Word document to the following email address:  abstracts@legacy.coloncancerfoundation.org. Abstracts should include a title, and name(s) of all author(s) and their institution or organization affiliation.  The name of the presenting author should be underlined.  The body of the abstract should not exceed 350 words.  See below for guidelines specific to the body of research and program abstracts.

RESEARCH ABSTRACTS  Abstracts describing scientific research on early age onset colorectal cancer should organize the content using the following subheadings:  Background, Methods, Results, and Conclusions. One data table is permitted per abstract. Illustrations and figures are not permitted. Define all abbreviations. Include the abstract title, full names and institutional affiliations of all authors, and email address of the corresponding author at the top of the abstract. Underline the name of the presenting author. Abstracts must not contain copyrighted material unless permission has been obtained by the author. Indicate at the bottom of the page if the abstract has been presented elsewhere and at what meeting. Submitted abstracts not meeting the above specifications will be returned. Any and all relevant conflicts of interest need to be noted at the bottom of the abstract.

Any questions regarding abstract submission should be directed to abstracts@legacy.coloncancerfoundation.org

PROGRAM ABSTRACTS Abstracts describing programs focused on any aspect of early age onset colorectal cancer should organize the content using the following subheadings:  Program Objectives, Audience, Program Description, Future Directions.  One table is permitted per abstract.  Illustrations and figures are not permitted. Define all abbreviations. Include the abstract title, full names and institutional affiliations of all authors, and email address of the corresponding author at the top of the abstract. Underline the name of the presenting author. Abstracts must not contain copyrighted material unless permission has been obtained by the author. Indicate at the bottom of the page if the abstract has been presented elsewhere and at what meeting. Submitted abstracts not meeting the above specifications will be returned. Any and all relevant conflicts of interest need to be noted at the bottom of the abstract.

Any questions regarding abstract submission should be directed to abstracts@legacy.coloncancerfoundation.org

POSTER PRESENTATION SESSIONS

Poster presentations will provide an opportunity for interchange of ideas between the presenter and EAO CRC Summit attendees in his/her study. The poster should be outlined so the research can be understood without an oral explanation as a poster may also be viewed when the author is not present.

Poster location to be determined. Posters will be easily accessible and available for viewing for the duration of the EAO CRC Summit including a reception to be held on the evening of May 11.

Set-Up: Will take place on Tuesday, May 11 time TBD. Each poster will be assigned a sequential number. Locate your assigned poster board and mount your poster within the time noted on the instructions received once accepted. Pushpins will be provided in the area by the Moderators.

Format of poster is LANDSCAPE (horizontal).

Regular Poster Size Limitations: TBD

Photos, Charts, and Graphs: Charts, drawings, and illustrations should be similar to those you would use in making PowerPoint slides. If photographs are used, please have them processed with a matte or dull finish.

Contact Information: Please clearly print 1 email address on your poster for attendees to refer to should they have any questions or comments at a time when you are not standing with your poster. If you do not wish to print your own email address, please list another email address for an appropriate contact person for your abstract.

Poster Material: The poster can either be made on 1 sheet (rollup) or in several small sections. Do NOT mount illustrations on heavy cardboard because they may be difficult to keep in position on the poster board.

Take-Down: Will take place on Tuesday, May 11, 9:30 PM. Please disassemble your posted materials at the end of the EAO CRC Summit. Any materials left on the poster board at the end of the session will be removed and disposed of.

AWARDS AND JUDGING

As part of the abstract review process, the poster review committee will identify the top-ranking abstracts. EAO CRC Summit attendees will also have the opportunity to review posters and vote for the People’s Choice Award. The top three abstracts and the People’s Choice Awardee will be recognized during the EAO CRC Summit poster session and during the closing remarks/award ceremony.

THE DR. THOMAS K. WEBER, MD, FACS NEXT GENERATION RESEARCH SCHOLAR AWARD 

The Colon Cancer Foundation and the EAO-CRC Planning Committee are pleased to announce The Dr. Thomas K. Weber, MD, FACS Next Generation Research Scholar Award aimed to promote and recognize excellence in research focused on early-onset colorectal cancer. This award will provide $2,500 to cover meeting registration, travel, and accommodation expenses to the 6th Annual EAO-CRC Summit on April 22-23, 2020 in New York City.

Dr. Thomas Weber was a staunch supporter of young or early career investigators – always the first to encourage them to be big and bold with their ideas. He believed it is imperative that we bring them into the heart of our discussions at the earliest possible stage to ensure progress continues on these most pressing and urgent issues.

As he himself wrote, ” How can we best provide effective enduring mentorship of the next generation of clinicians and scientists who will take on the clinical and scientific challenges.” We are quite certain he meant to include those who will continue to advocate for the patients and caregivers – who will give them a voice.

The Dr. Thomas K. Weber, MD, FACS Next Generation Research Scholar Award Criteria:

The goal of this award is to recognize excellence in clinical research focused on early age onset colorectal cancer. In providing this award, the CCF seeks to both support and promote EAO-CRC research. The CCF has a special interest in the biology of early age of onset. However, research into other areas of early age onset colorectal cancer (e.g., novel treatments, innovative minimally invasive screening technologies) will also be considered.

WHO SHOULD SUBMIT? 
The following are eligible to apply:
Trainees (i.e., postdoctoral fellows, residents, and clinical fellows);
Junior faculty (within one year of first independent faculty appointment); or
Junior genetic counselors (within one year of completion of training).

ACCOMMODATIONS

The Westin Times Square

270 W 43rd St, New York, NY 10036

The Colon Cancer Foundation has reserved a small block of rooms at the The Westin Times Square. Please use the link below to make your reservation. Additional rooms may be available by contacting the hotel directly at (212) 247-0300.

https://www.marriott.com/event-reservations/reservation-link.mi?id=1576182096305&key=GRP&app=resvlink

Last Day to Book: Tuesday, March 31, 2020

Special group rate:$299 USD

LIBRARY

CCF Articles

Global Patterns and Trends in Colorectal Cancer
Incidence in Young Adults

EAO CRC Abstracts

The Fifth Annual
EAO-CRC Summit
(2019)

Abstracts

EAO CRC 2019 Agenda

The Fifth Annual
EAO-CRC Summit
(2019)

Agenda

EAO CRC 2019 Video

How Nurses Can Support Physicians
in Identifying Colorectal Cancer Risk
(2019)

Videos

EAO CRC 2019 Video

Be Alert to the Symptoms
of Colorectal Cancer
(2019)

Videos

EAO CRC 2019 Video

The Fifth Annual
EAO-CRC Summit
(2019)

Videos

EAO CRC 2019 Photo Gallery

The Fifth Annual
EAO-CRC Summit
(2019)

Photo Gallery

EAO CRC 2019 Event Slides

The Fifth Annual
EAO-CRC Summit
(2019)
Session i Slides

EAO CRC 2019 Event Slides

The Fifth Annual
EAO-CRC Summit
(2019)
Session ii Slides

EAO CRC 2019 Event Slides

The Fifth Annual
EAO-CRC Summit
(2019)
Session iii Slides

EAO CRC 2019 Event Slides

The Fifth Annual
EAO-CRC Summit
(2019)
Session iv Slides

EAO CRC 2019 Event Slides

The Fifth Annual
EAO-CRC Summit
(2019)
Session v (part one) Slides

EAO CRC 2019 Event Slides

The Fifth Annual
EAO-CRC Summit
(2019)
Session v (part two) Slides

EAO CRC 2019 Event Slides

The Fifth Annual
EAO-CRC Summit
(2019)
Session vi Slides

EAO CRC Archives

The Fourth Annual
EAO-CRC Summit
(2018)

EAO CRC Archives

The Third Annual
EAO-CRC Summit
(2017)

Optimizing Outcomes For EAO-CRC

EAO CRC Archives

The Third Annual
EAO-CRC Summit
(2017)

Finding The Ideal State Of Wellness

EAO CRC Archives

The Third Annual
EAO-CRC Summit
(2017)

Navigating The Survivorship Landscape

EAO CRC Archives

The Second Annual
EAO-CRC Summit
(2016)

EAO CRC Archives

The First Annual
EAO-CRC Summit
(2015)

CCF Articles

(via New York Times)

CCF Articles

(via New York Times)

EAO CRC Archives

2020 Summary Report
EAO-CRC Summit
(2020)

EAO CRC Archives

2019 Summary Report
EAO-CRC Summit
(2019)

EAO CRC Archives

EAOCRC – National Clinical Alert – 2021